(R)- (-)-4- (3-ІЗОТІОЦІАНАТОПІРОЛІДИН-1-ОВИЙ)-7-НІТРО-2,1,3-БЕНЗОКСАДІАЗОЛ [МАРКУЮЧИЙ РЕАГЕНТ ВЕРХ ДЛЯ ВИЗНАЧЕННЯ ЕНАНТІОМЕРНОГО НАДЛИШКУ], >98.0% (HPLC)
A5577-100MG
Виробник: Tokyo Chemical Industry Co., Ltd.
Номер продукту: A5577
Назва реагенту: (R)-(-)-NBD-Py-NCS [=(R)-(-)-4-(3-Isothiocyanatopyrrolidin-1-yl)-7-nitro-2,1,3-benzoxadiazole] [HPLC Labeling Reagent for e.e. Determination]
Область застосування: Для речовин, що місять аміногрупу
Техніка: ВЕРХ з флуоресцентним детектором
Опис: The compound A5577 is an HPLC fluorescence labeling reagent for optical purity determination. This compound easily reacts with amino groups, which are directly linked to an asymmetric carbon atom, and produces diastereomers of thiourea. These diasteromers can be separated by reversed phase HPLC, and an excellent chromatogram can be obtained by fluorescence detection at the excitation and emission wavelengths of 488 nm and 59 nm, respectively.
Since both (R)- and (S)-isomers of the derivatization reagents are commercially available on the
market, it is possible to change the elution order of the derivatized diastereomers by selecting either
enantiomer of the derivatization reagent. Thus, an enantiomer of the amino-compound, whose existing
quantity is very small, can be eluted out first and quantified with high precision. Moreover, there are
reports for the application of these isomers to Edman Degradation.
market, it is possible to change the elution order of the derivatized diastereomers by selecting either
enantiomer of the derivatization reagent. Thus, an enantiomer of the amino-compound, whose existing
quantity is very small, can be eluted out first and quantified with high precision. Moreover, there are
reports for the application of these isomers to Edman Degradation.
CAS No: 163927-29-5
Formula: C11H9N5O3S
MW: 291.29
MDL No: MFCD02093434
Термін придатності: 12 місяців з дати отримання товару за умови дотримання вимог щодо його зберігання, що зазначенні в п. 7 SDS
Comments (0)