BioZen Biologics LC Columns

Explore Biozen LC Portfolio

With a new titanium BioTi™ biocompatible hardware to minimize priming, four particle platforms for optimal versatility and nine particle chemistries to maximize selectivity and sensitivity, Biozen UHPLC/HPLC columns are seamlessly designed to bring peace of mind to your analysis of biologics through:

Charge Variant Analysis

Aggregate Analysis

Peptide Mapping

Intact Mass

Intact and Fragment Analysis

Glycan Analysis

Peptide Quantitation

Drug Antibody Ratio (DAR)

Oligonucleotide Characterization

Four Advanced Particle Platforms

All four of the Biozen particle platforms were individually designed and built by Phenomenex to take advantage of integral levels of performance, ruggedness, and reproducibility for protein characterization applications. Individually, each platform differs in the proprietary processing techniques used to control particle size and morphology:

1. Pore Controlled Technology - The Biozen dSEC columns are packed with low pore volume silica coupled with a proprietary hydrophilic diol-type bonded surface chemistry that prevents the silica surface from interacting with protein samples.
2. Monosized Polymeric Non-Porous - Meticulously controlled monosized particle technology secures incredible particle consistency that leads to improved and reliable efficiency. This innovative non-porous particle serves as the perfect backbone for complex ion-exchange chemistries.
3. Core-Shell Technology - Using sol-gel processing techniques that incorporate nano structuring technology, a durable, homogeneous porous shell is grown on a solid silica core. This highly optimized process combined with industry leading column packing technology produces highly reproducible columns that generate extremely high efficiencies and sensitivity.
4. Thermally Modified Fully Porous - Through a proprietary thermal processing series of steps, we eliminate micropores and further improve consistency, column efficiency, inertness, ruggedness, and reproducibility.